The science behind Lunia
Every ingredient in Lunia is backed by peer-reviewed, human clinical research on sleep, relaxation, and stress regulation. We link directly to the original published study for every claim below, no exceptions.
Explore the researchResearch, organized the way you'd actually read it
Magnesium bisglycinate and insomnia severity
A randomized, double-blind, placebo-controlled trial found magnesium bisglycinate produced a significantly greater reduction in insomnia severity than placebo over four weeks.
Read the study →Sleep onset latency in older adults
A systematic review of three trials found magnesium supplementation reduced sleep onset latency by roughly 17 minutes versus placebo.
Read the study →Magnesium, anxiety, and sleep quality
Most included studies reported improvement in either sleep quality or self-reported anxiety after magnesium supplementation.
Read the study →L-theanine and sleep quality
A review of 19 studies found L-theanine significantly improved subjective sleep onset latency and overall sleep quality scores.
Read the study →L-theanine and stress-related symptoms
Four weeks of L-theanine supplementation significantly reduced depression and trait-anxiety scores versus placebo.
Read the study →L-theanine in adults with moderate stress
28 days of supplementation was safe and significantly reduced perceived stress while improving sleep quality and attention.
Read the study →The original study linking apigenin to calming receptor activity
The foundational laboratory study that first identified apigenin, isolated from Matricaria recutita (chamomile), as a ligand for central benzodiazepine receptors. Apigenin competitively displaced flunitrazepam from GABA-A receptors and produced mild anxiolytic and sedative effects, without the muscle-relaxant or anticonvulsant effects typical of benzodiazepine drugs.
Read the study →How apigenin works: a review of the mechanistic evidence
A broad review of apigenin's experimental and mechanistic evidence, including its effects on pro-inflammatory signaling pathways such as TNF-alpha and IL-6 that are linked to disrupted sleep. Synthesizes laboratory and preclinical evidence rather than new human trial data.
Read the study →The largest pooled evidence on chamomile and sleep to date
A systematic review and meta-analysis of 10 clinical trials found chamomile supplementation significantly reduced Pittsburgh Sleep Quality Index scores and the number of night-time awakenings. Total sleep duration and daytime functioning were not significantly improved.
Read the study →Apigenin at the intersection of sleep and aging
A review examining apigenin's proposed mechanisms for sleep support, including GABA-A receptor modulation, and its emerging relationship to cellular aging pathways. Synthesizes existing preclinical and clinical evidence rather than presenting new trial results.
Read the study →Emerging research: magnesium and apigenin together
A preclinical study found that magnesium and apigenin combined increased sleep duration in mouse models by 32 to 44 percent, more than either ingredient alone, linked to reduced inflammatory signaling in the brain. This is animal research, not yet tested in humans.
Read the study →Four filters, every study, no exceptions
Human trials first
We prioritize randomized controlled trials over animal or in-vitro data.
Peer-reviewed only
Every source has passed independent scientific review before publication.
Direct linking
We link straight to the original paper, never a search page or summary.
Claims reviewed
Every statement is checked against FDA guidance before it's published.
Common questions about our research
Is this tested on the finished Lunia formula or just the ingredients?+
The studies below evaluate our key ingredients individually, as researched by independent scientists. We'll publish product-level trials here as soon as they're complete.
What does peer-reviewed mean?+
It means the study was reviewed by independent experts in the field before publication, a standard check on methodology and conclusions.
How do you choose which studies to cite?+
We prioritize randomized controlled trials and systematic reviews in reputable journals, and we link directly to the source every time.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Information on this page is for educational purposes and is not a substitute for medical advice.